After you flip to 12/12 you have 3 weeks or more of vege growth before it slowly stops stem elongation and leaf growth (vegetative growth).
So, it will grow back at this point still... if you want to heavily defoliate it, you can do so and expect it to regrow.
Less is more with defo... improve air flow if concerend about microbial growth... maybe, helping some lower bud sites with greater light penetration is a net benefit? I think that last one depends on context a bit... if you do extractions/cooking etc, the larfy stuff is nothing but a boon to you and hardly impacts upper nugs. But, the maximized use of light is the portion receiving strongest light, which is your canopy. if you want no larf, lollipopping and a little extra defo might be for you.