Oh absolutely not! These leaves are perfect for the veg state and are necessary for strong growth in the plant. The time you want to start considering defoliation is at the beginning of flower but certainly not before... If the leaves are really TOO big (and yours are not), you can always just tuck them under but don't trim them off.
Before you embark on any defoliation, give this article a read - it talks about the when, why and how of it all and makes a lot of sense... https://www.growweedeasy.com/nebulas-super-simple-3-step-defoliation-tutorial
The plant looks terrific! Good job so far but don't stunt her by doing things that don't need to be done!
Good luck...