looks like too much. nute burn imo. ive used biobizz every grow until my current. that look you see I always saw if any of the water with nutes splashed a leaf. that leaf always did that. so maybe that's it. or just over feeding. with bio bizz yu are best to only use nutrients every other or every 1/3 water. took me a while to understand . but just use only water for next 2 feedings and reevaluate. I like to take off the leaves that are messed up so I can judge the new growth rather than the one that's burnt
Yup... she's getting deficient in phosphorus.... the pH needs to be lowered to about 6.2-6.4 in a soil grow (5.5-6.2 for hydro) and you need to provide more PK as soon as possible.
Good luck....