Leaf pest issues

Maybe septoria (fungus). Possibly, but unlikely calcium deficiency. The problem appears to start with yellowing, then spots then holes. If sit progressed from yellowing to holes it’s Septoria, not insects. Just IMHO.

You've a nest of something. To find your lil drop-ins in suggest you lay stickies of some sort (although outdoors you'll have to get creative) But, to find the fault. You got find the culprits. Most likely. They're night attackers. As if it is past related that much damage. You'd see something Traps, plants/dishes of soap water around, place growth around them. Hopefully you'll catch a few. Just an idea. Good luck. Hope you solve this. She can't take much more of this. As them leaves are well, let's say, not going at full steam.

Mouse is 💯 right , it’s a genetic mutation that I’ve had before kinda like the leaves are coming out stuck together and they end up a bit mangled and variegated. In some cases it will grow out and be normal in others it will give you weird looking airy buds but I’d deffo grow it out it might end up doing something cool

I don't recognize it. could be from many different things. Best to know what pests are local in your area and work down from there. Can always try a broad spectrum insecticidal spray on the plant as its still in veg and then look for dead bodies of the bugs to find out what one it is. Or could try to place some sticky traps to see if they catch anything. There is a chance it is not from bugs but environment/plant. If its only on one plant and not the others, it might be a off mutation or sensitivity to something. Good Luck!