Question about mainlining

The way the plant responds is when you remove lower branches the top speeds up growth, on a sativa, that's not exactly the best thing as they already stretch quite a bit and the node spacing would be large..so to counteract this response, a different approach is required.. the more tops,the more growth suppressing hormone being produced the slower the other tops grow.. leaving lower branches also contributes to this up to the point where flower production begins to increase speed..at which point a lolipop of the unnecessary popcorn branches is due, the plant is already slowing down it's upward growth at this point and the pruning won't affect the node spacing very much.. Outdoors, with a sativa, if mainlining, consider how flexible a sativa is compared to indica.. so if you lay it down too soon, the tips become suppressed to early and the side branches assume apical dominance..so let them stretch up a few feet before laying down your best branches, taking advantage of the sativa stretch to space your side branches far enough apart that they don't crowd and give you air circulation issues..this way the soon to be uprights have enough space to grow freely down the mainline.. indica, similar approach but be more careful laying down the manifolds on those..