Has anyone tried Ethephon containing products such as Florel?

Whatever you do, DO NOT smoke anything sprayed with this super toxic and residual chemical! It is likely to cause cancer!

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With some online inquiry, I found that a foliar dosage for "Florel" may be ~30 mL/gallon water. Assuming the information on the label (listed at 3.9% Ethephon), this makes the plants dose approximately 1.17 mL ethephon/gallon or 1.64 grams/gallon. So, you spray a gallon of this solution on your plants... Let's say you will consume the entirety of the grow across a timeframe of 3 months: leaves, stems, and all, (you obviously won't lol) and let's also say 100% of the ethephon you apply stays on or in the plant until consumption (It won't, in the plant it is metabolized to ethylene, and it isn't actually persistent in the environment, but I can't say the same for a grow tent). Basically, we will just assume you will consume 100% of the ethephon you've applied across a timeframe of 3 months. In the given case above, you would be consuming the entirety of 1.64 grams across 90 days, or 18.22 milligrams of ethephon per day. If you weigh 60kg, you are consuming 0.304 mg/kg body weight per day. A pubchem source tells us "The overall NOAEL (No Observed Adverse Effect Level) for short-term (28 days) effects of ethephon in humans exposed for at least 2 weeks was 0.5 mg/kg bw per day." Now keep in mind this number of 0.304 mg/kg bw per day was calculated assuming 100% of what was applied in one application will stay in the final product. (In reality this is not the case, as some will be absorbed into the plant and metabolized to ethylene, some will miss the plant entirely or will be washed off during your other foliar applications.) Also, you must keep in mind that these numbers are regarding direct oral consumption of ethephon, not inhalation of the smoke byproducts. Judge these numbers as you will, but according to my logic, you could theoretically "safely" drink 1/3 of the solution you prepare across 30 days, as five women had received 2.2 mg/kg bw per day for 28 days. TLDR: I wouldn't apply it more than once per grow, if at all. https://pubchem.ncbi.nlm.nih.gov/source/hsdb/2618#section=Human-Toxicity-Excerpts-(Complete) https://inchem.org/documents/jmpr/jmpmono/2002pr05.htm#1.4 Here are some human volunteer tests sourced from the inchem link: When volunteers were given ethephon orally at a dose of 0.17 or 0.33 mg/kg bw per day (in three divided doses), the only significant finding was inhibition of plasma cholinesterase activity. No gross symptoms or changes in haematological, clinical chemical or urine end-points were associated with treatment (Weir, 1977a). In another study, 10 male and 10 female volunteers received ethephon orally by capsule at 0.5 mg/kg bw per day for 16 days. Plasma cholinesterase activity was significantly inhibited, but no gross symptoms or changes in haematological, clinical chemical or urine end-points were associated with treatment (Weir, 1977b). In a third study, five male volunteers received a dose of 1.5 mg/kg bw per day and five women received 2.2 mg/kg bw per day for 28 days, followed by a 14-day dose-free period. Neither plasma nor erythrocyte cholinesterase activity was inhibited, but transient symptoms consistent with inhibition of acetylcholinesterase activity, including urinary urgency and gastrointestinal effects, were reported. The overall NOAEL for short-term effects of ethephon in humans was 0.5 mg/kg bw per day (Reese, 1971, 1972). "After considering the previous evaluation of ethephon, the new data submitted and recent publications in the open literature, the Meeting established an acute RfD of 0.05 mg/kg bw on the basis of the NOAEL of 0.5 mg/kg bw in studies in humans given repeated doses and a 10-fold safety factor"

Id also be more prone to picking off all pollen sacks as well to try and get the most out of my weed vs spray this.