sure.. the vermiculite even adds a little available silicon, too.
check out some wickedtstyx gows with the all perlite and recirculating drip irrigation system... can't grow much more effciciently than that.
growdiaries.com/grower/wicked-stix
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@wicked_stix...
hydro is the simples thing to do as far as the nutes... 650-750ppm mix every irrigation and you are golden. (or ebb/flow, drip whateer). i have a ppm beakdown for my soilless grow. it'll be same as for "hydro". sceenshot in any diary, just about.. my full power mix is 720ppm.. what is shown is merely a ballpark that shifts as needed based on observanaces from plant and stage of life.. generally just requires adjusing N down a bit in bloom by 5-10% . if i give any more p or k it burns the plant at any stage.