I wonder whether trimming the lower (big) leaves would be beneficial? Because they’re all shaded now but maybe they participate in the transpiration process at night?
If they aren't covering any potential bud nodes, I'd leave them. Only reasons to defoliate is to increase light to bud nodes and airflow around the center of the plant.
I hope this helps.
I'm going to give you an article to read that has become my "bible" when it comes to the subject of defoliation.... I think you might find it very, very useful!
https://www.growweedeasy.com/nebulas-super-simple-3-step-defoliation-tutorial
Good luck!