If harvested when only some of the trichomes are cloudy, the buds will be small and not have the full aroma/flavor profile youâre trying to achieve. The high will be energetic, speedy and sometimes paranoid. This is due to the high levels of THC, and low levels of CBD / CBN which offset the THCâs effects with their relaxing, anti-anxiety properties. When most of the trichomes become cloudy, youâre about ready to harvest. At this stage, the buds are in their full maturity, with the classic âweed highâ effect that youâre looking for. The high will be both intense and euphoric, as well as having strong pain relieving, anti-nausea and anxiety-treating effects