I started with only NPK (2 bottle) => some strain taste awful without flowering and terpene boost
Then added flowering and terpene boost ( + 1 bottle) => totally change taste for some strain, and tend to make other sweeter and smoother
Then added comfort, whole health additives ( + 3 bottle). => does what it's say as well, overall health better, strains sensitive to specific micro-nutrient need especially appreciate.
over two year and a few grow cycles, some strains have grown with and without, definitely worth it.