Those bumps at the node joints are most likely normal. Common causes: (1) adventitious root primordia, small root nubs that form on stems when humidity is high or the stem is bent or tied, (2) callus tissue where branches were bent or trained, which thickens the joint to carry the load. Neither is harmful. Check that the bumps are firm and green with no pests, mold or oozing, and that ties aren't cutting into the stem. If they are, loosen them. If humidity is very high, bring it down a bit in late flower for mold safety. A landrace like Chitral also tends to have thick, knobby nodes naturally