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@CalGonJim
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8/4 130am. MONDAY. just AN from now on, no more aminos they will just ad N at this point and counter flowering. 🚨🚨8/4 12:30pm !!! FOR HUMANS!!!!!!🚨🚨👨‍🔬Combining **L-glutamine**, **proline**, **essential amino acids (EAAs)**, **glycine**, and **trimethylglycine (TMG)** in your supplement regimen, as seen in the nutrient mix you described for your cannabis grow, can have significant effects on human health, particularly given your positive experience with methylene blue (“I feel great after I take it”). Since you’re asking about the benefits for yourself (not plants), I’ll focus on how these compounds may contribute to your well-being, their synergistic effects, and how they might align with the energy and mood boost you’ve reported. I’ll also consider the context of your previous questions, including the nitric oxide (NO) precursors and methylene blue, to provide a comprehensive picture. The response will be concise yet thorough, addressing mechanisms, benefits, and potential considerations. ### Overview of Each Component and Their Benefits for Humans 1. **L-Glutamine (500 mg in your mix)**: - **Role**: A conditionally essential amino acid, critical for gut health, immune function, and muscle recovery. - **Benefits**: - **Gut Health**: Supports intestinal lining repair, reducing leaky gut and improving digestion, which can enhance overall well-being and energy. - **Immune Support**: Fuels immune cells (e.g., lymphocytes), boosting resilience, especially during stress or illness. - **Muscle Recovery**: Reduces muscle soreness and supports protein synthesis, beneficial if you exercise or are physically active. - **Brain Health**: Serves as a precursor to neurotransmitters like glutamate, potentially improving focus and mood. - **Relevance to You**: The energy and mood boost you feel may partly stem from glutamine’s role in reducing inflammation and supporting brain function. 2. **Proline (100 mg in your mix)**: - **Role**: A non-essential amino acid involved in collagen synthesis, tissue repair, and antioxidant defense. - **Benefits**: - **Joint and Skin Health**: Promotes collagen production, supporting joint flexibility, skin elasticity, and connective tissue repair. - **Cardiovascular Health**: Supports arterial wall integrity, potentially complementing the NO precursors in your mix (L-arginine, L-citrulline). - **Stress Resistance**: Acts as an osmoprotectant, helping cells manage oxidative stress, which may contribute to your “feeling great.” - **Relevance to You**: Proline’s low dose may subtly support tissue health and stress resilience, enhancing your overall vitality. 3. **Essential Amino Acids (EAAs, 300 mg in your mix)**: - **Role**: EAAs (e.g., leucine, lysine, methionine) are amino acids the body cannot synthesize, essential for protein synthesis and metabolic functions. - **Benefits**: - **Muscle Maintenance**: Stimulates muscle protein synthesis, aiding recovery and preventing muscle loss, especially during exercise or aging. - **Energy and Mood**: EAAs like leucine support energy metabolism, while tryptophan and phenylalanine are precursors to serotonin and dopamine, potentially boosting mood. - **Metabolic Health**: Supports insulin sensitivity and nutrient metabolism, contributing to sustained energy. - **Relevance to You**: EAAs may enhance your energy and mood by supporting muscle recovery and neurotransmitter production, aligning with your positive response to the mix. 4. **Glycine (1 g in your mix)**: - **Role**: A non-essential amino acid involved in collagen synthesis, neurotransmitter regulation, and detoxification. - **Benefits**: - **Sleep and Mood**: Acts as an inhibitory neurotransmitter, promoting relaxation and improving sleep quality, which can enhance mood and energy. - **Cognitive Health**: Supports NMDA receptor function, potentially improving memory and focus. - **Collagen and Joint Health**: Like proline, supports connective tissue and skin health. - **Detoxification**: Aids in glutathione production, reducing oxidative stress and supporting liver function. - **Relevance to You**: Glycine’s calming effects and antioxidant support may contribute significantly to your “feeling great,” especially if you experience better sleep or reduced stress. 5. **Trimethylglycine (TMG, 1 g in your mix)**: - **Role**: Also known as betaine, TMG is a methyl donor involved in homocysteine metabolism and cellular protection. - **Benefits**: - **Cardiovascular Health**: Lowers homocysteine levels, reducing heart disease risk, and may synergize with NO precursors for better blood flow. - **Exercise Performance**: Enhances hydration and muscle endurance, potentially improving physical energy. - **Liver Health**: Supports fat metabolism and detoxification, reducing liver stress. - **Mood and Stress**: Methylation supports neurotransmitter synthesis, potentially boosting mood. - **Relevance to You**: TMG’s role in energy metabolism and methylation may amplify the mood and energy benefits you’re experiencing. ### Synergistic Benefits of the Combination The combination of L-glutamine, proline, EAAs, glycine, and TMG, alongside the NO precursors (L-arginine, L-citrulline, etc.) and methylene blue from your mix, creates a synergistic effect that likely explains why you “feel great”: 1. **Enhanced Energy and Recovery**: - **Glutamine, EAAs, and TMG**: Support muscle protein synthesis, energy metabolism, and recovery, reducing fatigue and boosting physical vitality. Beta-alanine (from the NO capsule) buffers lactic acid, enhancing exercise endurance. - **NO Precursors**: L-arginine and L-citrulline increase NO production, improving blood flow and oxygen delivery to muscles and brain, enhancing energy and focus. - **Methylene Blue**: As you noted, methylene blue enhances mitochondrial efficiency, boosting ATP production, which complements the energy-supporting effects of glutamine, EAAs, and TMG. 2. **Mood and Cognitive Boost**: - **Glycine and EAAs**: Glycine promotes relaxation and sleep, while EAAs (e.g., tryptophan, phenylalanine) support serotonin and dopamine production, enhancing mood and mental clarity. - **TMG**: As a methyl donor, supports neurotransmitter synthesis and reduces homocysteine, which is linked to mood disorders. - **Methylene Blue**: Its mild MAO inhibition may increase serotonin and dopamine levels, amplifying the mood benefits you’re experiencing. 3. **Stress Reduction and Resilience**: - **Proline, Glutamine, and Glycine**: Act as antioxidants and osmoprotectants, reducing oxidative stress and supporting cellular health under physical or mental stress. - **TMG**: Enhances methylation, supporting stress resilience and detoxification. - **Methylene Blue**: Its antioxidant properties may reduce cellular stress, complementing the other compounds. 4. **Cardiovascular and Tissue Health**: - **Proline, Glycine, and TMG**: Support collagen synthesis and cardiovascular health, improving joint, skin, and arterial function. - **NO Precursors**: Enhance vasodilation, improving blood flow and nutrient delivery, which may contribute to your overall sense of well-being. ### Why You Feel Great Your positive response (“I feel great”) likely stems from the combined effects of: - **Mitochondrial and Energy Boost**: Methylene blue and glutamine enhance ATP production and energy metabolism, giving you a physical and mental lift. - **Neurotransmitter Support**: Glycine, EAAs, TMG, and methylene blue support serotonin, dopamine, and GABA activity, improving mood, focus, and relaxation. - **Reduced Stress**: Proline, glutamine, and TMG combat oxidative stress and support recovery, reducing fatigue and enhancing resilience. - **Improved Blood Flow**: NO precursors increase circulation, delivering more oxygen and nutrients, which may enhance energy and cognitive clarity. The doses in your mix (500 mg glutamine, 100 mg proline, 300 mg EAAs, 1 g glycine, 1 g TMG) are within typical supplemental ranges, suggesting a balanced approach that avoids overload while providing cumulative benefits. ### Considerations and Precautions 1. **Dosage Safety**: - Your doses are moderate and generally safe for most adults, but long-term high doses of TMG (1 g daily) or glutamine (500 mg daily) may stress the liver or kidneys in sensitive individuals. Typical supplemental doses are 500–3,000 mg for TMG and 5–10 g for glutamine, so you’re on the lower end. - Methylene blue (2 drops of 5% solution ≈ 5 mg) is a low dose, but its long-term use lacks extensive human studies. Monitor for side effects like nausea or dizziness. 2. **Interactions**: - **Methylene Blue and SSRIs**: Methylene blue is a mild MAO inhibitor and can cause serotonin syndrome if combined with SSRIs or other serotonergic drugs. Consult a doctor if you’re on such medications. - **NO Precursors**: L-arginine and L-citrulline may lower blood pressure, so monitor if you have hypotension or take related medications. - **TMG and Methylation**: High TMG doses may overstimulate methylation, potentially causing anxiety in some individuals. Your 1 g dose is moderate but worth monitoring. 3. **Individual Response**: - Your positive response suggests your body responds well to this mix, possibly due to baseline deficiencies (e.g., in glycine or glutamine) or high metabolic demands (e.g., from exercise or stress). Genetic factors affecting methylation (e.g., MTHFR mutations) may make TMG particularly effective for you. 4. **Nutrient Timing**: - Taking this mix in the morning (as implied by 2:47 AM) aligns with boosting energy and focus for the day. However, glycine’s calming effects might be better utilized at night for sleep support. Consider splitting doses (e.g., glycine in the evening, others in the morning). ### Recommendations - **Optimize Timing**: Take glutamine, EAAs, and TMG in the morning for energy and recovery, and glycine in the evening for relaxation and sleep. Proline can be taken anytime due to its structural role. - **Monitor Effects**: Track specific benefits (e.g., energy, mood, sleep, exercise recovery) to identify which compounds drive your “feeling great.” If methylene blue is key, its mitochondrial and mood effects may be central. - **Hydration and Diet**: Ensure adequate hydration and a balanced diet, as amino acids and TMG increase metabolic demands. Pair with B vitamins (especially B6, B12, folate) to support methylation and amino acid metabolism. - **Consult a Professional**: Discuss this regimen with a doctor or nutritionist, especially regarding methylene blue and NO precursors, to rule out interactions or contraindications (e.g., G6PD deficiency for methylene blue). - **Adjust Doses if Needed**: If you notice side effects (e.g., jitteriness from TMG, GI upset from glutamine), reduce doses (e.g., 500 mg TMG, 250 mg glutamine) and reassess. ### Conclusion The combination of L-glutamine, proline, EAAs, glycine, and TMG likely contributes to your feeling great by boosting energy (via mitochondrial support and muscle recovery), enhancing mood (through neurotransmitter production), reducing stress (via antioxidant and osmoprotectant effects), and supporting cardiovascular and tissue health. Methylene blue and NO precursors from your mix amplify these benefits by improving mitochondrial function and blood flow. Your moderate doses are generally safe, but careful monitoring and medical consultation are advised, especially for methylene blue. If you’d like, I can search for recent studies or X posts on these supplements for human use, or tailor a dosing schedule based on your goals (e.g., energy, mood, recovery). Let me know how you’d like to proceed!🚨👨‍🔬. 8/4 1230pm. 8/5 12:50am HEY HARRISON SMITH, HARVEY WALL BANGER, GET IT?...IM SO GOOD. ANYHOW....FLUSH TODAY, FLORAKLEEN 5ML PER GALLON ALL OF THEM..... NO DONT PILLAGE ME AND IM LIKE NO! IM PILLAGING EVERYBODY, YOU INCLUDED. 8/5 3:51 AM I mixed up floor clean 5 mL per gallon doing bubbles first and then goats and the other girl next to it👍 8/5 7:10 AM I’ve been doing this since five and I can’t believe how high my EC was. It was off the chart like 6000 7000 so I had to do the flush. I’m never really bothered to do this before. I’m sure it’s gonna be a lot better. One of my last grows. The leaves were so full of garbage. Basically my weed smell like a hamburger so not exactly good but I’ll save it for people. I don’t like👍. Sometimes it doesn’t remember a whole paragraph. I just fucking typed piece of shit took me six hours to do four fucking plants.🤣💥💥💥 8/6 408am. The colas on the oldest of the 3 are AMAZING!!!! they are all small but MIGHTY!! 2 cola grows in 1 gallon seem to be about right. I will probably get 4oz dry from EACH!! That is really acceptable!!! For a home micro- grow where the goal is ALSO to grow as many different kinds, to get more seeds, which keeps the seed companies coming up with new strains!!!! The 1 gallon plastic pots are light, small bags of Soil Sunrise from online is easy to store, CLEAN! the bags of dirt it comes in are strong, and easy to wipe up when done. The 8qt fills several pots I also mix in about 4 8oz cups of Perlite per container to stretch the dirt out a bit. Soil Sunrise delivered by amazon is the only dirt that did NOT have bugs...I used to order HUGE bags of FF delivered from outdoor garden centers all over the country ...the bug infested HORROR, never again!!! 8/6 418am Also my body is starting to fail, I can feel it. If there is any discomfort there will be no more updates. thats life. doesnt it go by in a blink? I think to myself what a bullshit goblin & demon infested shithole of a world, cant dies soon enough. And death to the shitters of 1978!!!😡 Did you ever hear about the Tragedy of Darth Arnie and Christine? He's more Chrysler 1958 Plymouth Fury than man now...maybe I got the movies mixed up again....idk....
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Update - 4th July 2021 Just still flushing away. The colours that are coming out are crazy. I have edited some pics but not videos and the videos dont really pick up the colour. Its strange that it started completely green and then went darker and darker until it reached purple buds covered in trichomes. I am planning on harvesting both this plant and the purple punch today or tomorrow depending on when i can be bothered lol Tbh, its not hard because i dry trim so it's just a case of plucking off the fan leaves and hanging it in different branches.
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Strawberry Truffle - White Truffle x Red Pop & limited seed it came with Chem 91 x Red pop
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@Bigg_soum
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On veg the temperature is so high ≈32-35Cº.
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@alafmalaf
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Randomly decided to germinate bag seeds. Let's see where this goes!
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@rucucu94
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Disculpen las fotos, es que las saque para consultar. Bueno primero que nada fue una semana de mucha tormanta, lluvias y humedad. lo peor que nos puede pasar en floracion. Segundo intente hacer supercroping ya que las ramas seguian superando el tejido y les llegaba luz en la noche. Y me salio desastrozo, mi primera vez. Pero los otros punteros que superaban la altura, los hizo mi compañero que sabia hacerlo (No tengo foto, luego actualizo). Y Tercero que debido a la humedad se ven en las fotos como aparecio hongos, por lo que pude observar era solo ese poco, lo cual ya fue removido vamos a ver como continuamos.
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@gdogfunk
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Day 57 This should be the last week in veg. It might be a partial week...I'll make the call in a few days. I'm excited to see these babes flower!!! Day 58: Last day of VEG! I set the timer to 12/12 and lower the lights to 18". These babes are ready to switch, based on my past experience. I hope they don't shoot too much in the next couple of weeks! Flower time is here at last! Day 59: Flower day 1! Fed transistion week 1 nutes today. Day 61: The plants are stretching nicely and I expect to run out of room on the screen at the outer edges. Day 63: I'm really surprised how fast Shiskaberry caught up to her tentmate. She's got many bud sites, even after losing one of the mains. It might actually be a good thing I'm down a few tops, since the canopy is getting VERY full!
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Day37 05/08/24 Monday Feed today using de-chlorinated tap water pH 6. She has bounced back from topping so now applying LST this week. Day 39 07/08/24 Wednesday De-chlorinated tap water pH 6 today with calmag. Day 41 10/08/24 Saturday Feed today using de-chlorinated tap water pH 6 only. Day 42 11/08/24 Sunday End of week de-chlorinated tap water pH 6 with calmag. She has recovered well from topping and lst. Presenting a beautiful structure so far 😁 Picture and video update ✌️💚
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Recovering very well, noticeable growth daily. Topped, Lst, and pruned over the last week. Adjusted light height and spectrum to encourage more lateral growth. Hope I didn’t overdo it. The og kush(right) growing a little slow, strawberry gorilla(left) is an autoflower and its leaves are looking a little funky.
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Topped for the third time this week. They are really coming on well now. No problems everything is stable and looking good. 3 weeks till flower!!
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Set up Scrog in the start of the week. Foliar fed with CalMag + Iron 3 times this week. Defoliated lower shoots and fan leaves mid week. Raised ph in reservoir to 6.1 because the runoff was coming out at 5.2 ph. Now the runoff is at a steady 5.6 ph.
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@Filiaes
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26.05 Cleaned the Tank and changed the water. Beside that nothing special to say about that grow - everything is just beautiful and developing suiper well.
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DAY 71 F: Well a day overdue for the update but I have been a busy fellow in the real world. The Girls scout cookies have dried enough to be considered for jarring. They have finished so perfectly and so damn tacky too. They smell of sweet candy after a lollipop lick. So nice. I have been taking samples the past week of so and drying them . temptation won.lol Idont expect a huge yield from their size but the quality is bang on the money. The Amnesia haze ladies are so so close now . They are rock somid still and have really packed the trichs on , a little swelling has been noticable but not the second flush of pistils I was hoping for. #1 and 2 are going to be left until day 77 at least , so another week but the #3 lady has got to go into the dark period now I think. She was the girl I confused as a gsc too so had her dragon force very early in that respect. Seeing how faded out she has got during the last week has helped drive the decision to get her out now. She will be in the dark for 48 hours then trimmed for drying. They will all be fed just water now to use up the remaining nutes in the pots to the end. The critical cheese is in mid flush of her newest pistils and thankfully is swelling nicely due to that fact. She has a really fuel/ nail polish heavy aroma at present but I can smell the sweet tang too. She looks like her yield could be a good one for what looked like a gangly specimen for the past 12 weeks. Lol . One of criticals finest qualities I think. All in all a good week for the ladies if not a calm one. Let's see what next week brings. Be safe and well growmies.
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Kok gubresi sonlandirildi. Big bud ve b 52 ye 2 hafta aranin ardindan baslandi evet azot biraz fazla geldigini farkindayim fosfor ve potasyum agirlikli ilerlemeye devam ve bebeklerin bulunduklari ortam geregi boceklenme olmamasi icin duzenli sekilde neem yagi takviyesine devam ediyoruz emegimizin karsiligini alicagimiz bir hasat olucak kalite hic bir zaman tesaduf degildir..
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Day 49 and 50. With 28 to 42 days left(anticipating)went ahead and gave the girls some bloom nutrients. Decided to go with the pk13/14 from canna at 1 tsp per gallon. Each plant received 2 gallons and will repeat for the next two waterings. Decided against a top dressing as I amended the soil heavily at the start and would like to use up what’s in the soil already. To say the girls have grown up during summer camp is an understatement! Miss Harvey is an astonishing 44 inches tall and still growing. Ms. Fizz and the 91Grapes are both a very respectable 38 inches tall and still growing. Once these girls got their roots settled in it was off to the races and none of the are showing any interest in slowing down, I just think they will shift into flower overdrive! Or at least that’s my desire. update, bad news something chewed seven branches off my plants last night. pissed off. will include pictures later I love growing autoflowers. Their simple tenacity and vigor, their ability to flower at will and finish inside of three months is what keeps me coming back for more. Thank you Daz for some amazing plants.