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@CalGonJim
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8/4 130am. MONDAY. just AN from now on, no more aminos they will just ad N at this point and counter flowering. 🚨🚨8/4 12:30pm !!! FOR HUMANS!!!!!!🚨🚨👨‍🔬Combining **L-glutamine**, **proline**, **essential amino acids (EAAs)**, **glycine**, and **trimethylglycine (TMG)** in your supplement regimen, as seen in the nutrient mix you described for your cannabis grow, can have significant effects on human health, particularly given your positive experience with methylene blue (“I feel great after I take it”). Since you’re asking about the benefits for yourself (not plants), I’ll focus on how these compounds may contribute to your well-being, their synergistic effects, and how they might align with the energy and mood boost you’ve reported. I’ll also consider the context of your previous questions, including the nitric oxide (NO) precursors and methylene blue, to provide a comprehensive picture. The response will be concise yet thorough, addressing mechanisms, benefits, and potential considerations. ### Overview of Each Component and Their Benefits for Humans 1. **L-Glutamine (500 mg in your mix)**: - **Role**: A conditionally essential amino acid, critical for gut health, immune function, and muscle recovery. - **Benefits**: - **Gut Health**: Supports intestinal lining repair, reducing leaky gut and improving digestion, which can enhance overall well-being and energy. - **Immune Support**: Fuels immune cells (e.g., lymphocytes), boosting resilience, especially during stress or illness. - **Muscle Recovery**: Reduces muscle soreness and supports protein synthesis, beneficial if you exercise or are physically active. - **Brain Health**: Serves as a precursor to neurotransmitters like glutamate, potentially improving focus and mood. - **Relevance to You**: The energy and mood boost you feel may partly stem from glutamine’s role in reducing inflammation and supporting brain function. 2. **Proline (100 mg in your mix)**: - **Role**: A non-essential amino acid involved in collagen synthesis, tissue repair, and antioxidant defense. - **Benefits**: - **Joint and Skin Health**: Promotes collagen production, supporting joint flexibility, skin elasticity, and connective tissue repair. - **Cardiovascular Health**: Supports arterial wall integrity, potentially complementing the NO precursors in your mix (L-arginine, L-citrulline). - **Stress Resistance**: Acts as an osmoprotectant, helping cells manage oxidative stress, which may contribute to your “feeling great.” - **Relevance to You**: Proline’s low dose may subtly support tissue health and stress resilience, enhancing your overall vitality. 3. **Essential Amino Acids (EAAs, 300 mg in your mix)**: - **Role**: EAAs (e.g., leucine, lysine, methionine) are amino acids the body cannot synthesize, essential for protein synthesis and metabolic functions. - **Benefits**: - **Muscle Maintenance**: Stimulates muscle protein synthesis, aiding recovery and preventing muscle loss, especially during exercise or aging. - **Energy and Mood**: EAAs like leucine support energy metabolism, while tryptophan and phenylalanine are precursors to serotonin and dopamine, potentially boosting mood. - **Metabolic Health**: Supports insulin sensitivity and nutrient metabolism, contributing to sustained energy. - **Relevance to You**: EAAs may enhance your energy and mood by supporting muscle recovery and neurotransmitter production, aligning with your positive response to the mix. 4. **Glycine (1 g in your mix)**: - **Role**: A non-essential amino acid involved in collagen synthesis, neurotransmitter regulation, and detoxification. - **Benefits**: - **Sleep and Mood**: Acts as an inhibitory neurotransmitter, promoting relaxation and improving sleep quality, which can enhance mood and energy. - **Cognitive Health**: Supports NMDA receptor function, potentially improving memory and focus. - **Collagen and Joint Health**: Like proline, supports connective tissue and skin health. - **Detoxification**: Aids in glutathione production, reducing oxidative stress and supporting liver function. - **Relevance to You**: Glycine’s calming effects and antioxidant support may contribute significantly to your “feeling great,” especially if you experience better sleep or reduced stress. 5. **Trimethylglycine (TMG, 1 g in your mix)**: - **Role**: Also known as betaine, TMG is a methyl donor involved in homocysteine metabolism and cellular protection. - **Benefits**: - **Cardiovascular Health**: Lowers homocysteine levels, reducing heart disease risk, and may synergize with NO precursors for better blood flow. - **Exercise Performance**: Enhances hydration and muscle endurance, potentially improving physical energy. - **Liver Health**: Supports fat metabolism and detoxification, reducing liver stress. - **Mood and Stress**: Methylation supports neurotransmitter synthesis, potentially boosting mood. - **Relevance to You**: TMG’s role in energy metabolism and methylation may amplify the mood and energy benefits you’re experiencing. ### Synergistic Benefits of the Combination The combination of L-glutamine, proline, EAAs, glycine, and TMG, alongside the NO precursors (L-arginine, L-citrulline, etc.) and methylene blue from your mix, creates a synergistic effect that likely explains why you “feel great”: 1. **Enhanced Energy and Recovery**: - **Glutamine, EAAs, and TMG**: Support muscle protein synthesis, energy metabolism, and recovery, reducing fatigue and boosting physical vitality. Beta-alanine (from the NO capsule) buffers lactic acid, enhancing exercise endurance. - **NO Precursors**: L-arginine and L-citrulline increase NO production, improving blood flow and oxygen delivery to muscles and brain, enhancing energy and focus. - **Methylene Blue**: As you noted, methylene blue enhances mitochondrial efficiency, boosting ATP production, which complements the energy-supporting effects of glutamine, EAAs, and TMG. 2. **Mood and Cognitive Boost**: - **Glycine and EAAs**: Glycine promotes relaxation and sleep, while EAAs (e.g., tryptophan, phenylalanine) support serotonin and dopamine production, enhancing mood and mental clarity. - **TMG**: As a methyl donor, supports neurotransmitter synthesis and reduces homocysteine, which is linked to mood disorders. - **Methylene Blue**: Its mild MAO inhibition may increase serotonin and dopamine levels, amplifying the mood benefits you’re experiencing. 3. **Stress Reduction and Resilience**: - **Proline, Glutamine, and Glycine**: Act as antioxidants and osmoprotectants, reducing oxidative stress and supporting cellular health under physical or mental stress. - **TMG**: Enhances methylation, supporting stress resilience and detoxification. - **Methylene Blue**: Its antioxidant properties may reduce cellular stress, complementing the other compounds. 4. **Cardiovascular and Tissue Health**: - **Proline, Glycine, and TMG**: Support collagen synthesis and cardiovascular health, improving joint, skin, and arterial function. - **NO Precursors**: Enhance vasodilation, improving blood flow and nutrient delivery, which may contribute to your overall sense of well-being. ### Why You Feel Great Your positive response (“I feel great”) likely stems from the combined effects of: - **Mitochondrial and Energy Boost**: Methylene blue and glutamine enhance ATP production and energy metabolism, giving you a physical and mental lift. - **Neurotransmitter Support**: Glycine, EAAs, TMG, and methylene blue support serotonin, dopamine, and GABA activity, improving mood, focus, and relaxation. - **Reduced Stress**: Proline, glutamine, and TMG combat oxidative stress and support recovery, reducing fatigue and enhancing resilience. - **Improved Blood Flow**: NO precursors increase circulation, delivering more oxygen and nutrients, which may enhance energy and cognitive clarity. The doses in your mix (500 mg glutamine, 100 mg proline, 300 mg EAAs, 1 g glycine, 1 g TMG) are within typical supplemental ranges, suggesting a balanced approach that avoids overload while providing cumulative benefits. ### Considerations and Precautions 1. **Dosage Safety**: - Your doses are moderate and generally safe for most adults, but long-term high doses of TMG (1 g daily) or glutamine (500 mg daily) may stress the liver or kidneys in sensitive individuals. Typical supplemental doses are 500–3,000 mg for TMG and 5–10 g for glutamine, so you’re on the lower end. - Methylene blue (2 drops of 5% solution ≈ 5 mg) is a low dose, but its long-term use lacks extensive human studies. Monitor for side effects like nausea or dizziness. 2. **Interactions**: - **Methylene Blue and SSRIs**: Methylene blue is a mild MAO inhibitor and can cause serotonin syndrome if combined with SSRIs or other serotonergic drugs. Consult a doctor if you’re on such medications. - **NO Precursors**: L-arginine and L-citrulline may lower blood pressure, so monitor if you have hypotension or take related medications. - **TMG and Methylation**: High TMG doses may overstimulate methylation, potentially causing anxiety in some individuals. Your 1 g dose is moderate but worth monitoring. 3. **Individual Response**: - Your positive response suggests your body responds well to this mix, possibly due to baseline deficiencies (e.g., in glycine or glutamine) or high metabolic demands (e.g., from exercise or stress). Genetic factors affecting methylation (e.g., MTHFR mutations) may make TMG particularly effective for you. 4. **Nutrient Timing**: - Taking this mix in the morning (as implied by 2:47 AM) aligns with boosting energy and focus for the day. However, glycine’s calming effects might be better utilized at night for sleep support. Consider splitting doses (e.g., glycine in the evening, others in the morning). ### Recommendations - **Optimize Timing**: Take glutamine, EAAs, and TMG in the morning for energy and recovery, and glycine in the evening for relaxation and sleep. Proline can be taken anytime due to its structural role. - **Monitor Effects**: Track specific benefits (e.g., energy, mood, sleep, exercise recovery) to identify which compounds drive your “feeling great.” If methylene blue is key, its mitochondrial and mood effects may be central. - **Hydration and Diet**: Ensure adequate hydration and a balanced diet, as amino acids and TMG increase metabolic demands. Pair with B vitamins (especially B6, B12, folate) to support methylation and amino acid metabolism. - **Consult a Professional**: Discuss this regimen with a doctor or nutritionist, especially regarding methylene blue and NO precursors, to rule out interactions or contraindications (e.g., G6PD deficiency for methylene blue). - **Adjust Doses if Needed**: If you notice side effects (e.g., jitteriness from TMG, GI upset from glutamine), reduce doses (e.g., 500 mg TMG, 250 mg glutamine) and reassess. ### Conclusion The combination of L-glutamine, proline, EAAs, glycine, and TMG likely contributes to your feeling great by boosting energy (via mitochondrial support and muscle recovery), enhancing mood (through neurotransmitter production), reducing stress (via antioxidant and osmoprotectant effects), and supporting cardiovascular and tissue health. Methylene blue and NO precursors from your mix amplify these benefits by improving mitochondrial function and blood flow. Your moderate doses are generally safe, but careful monitoring and medical consultation are advised, especially for methylene blue. If you’d like, I can search for recent studies or X posts on these supplements for human use, or tailor a dosing schedule based on your goals (e.g., energy, mood, recovery). Let me know how you’d like to proceed!🚨👨‍🔬. 8/4 1230pm. 8/5 12:50am HEY HARRISON SMITH, HARVEY WALL BANGER, GET IT?...IM SO GOOD. ANYHOW....FLUSH TODAY, FLORAKLEEN 5ML PER GALLON ALL OF THEM..... NO DONT PILLAGE ME AND IM LIKE NO! IM PILLAGING EVERYBODY, YOU INCLUDED. 8/5 3:51 AM I mixed up floor clean 5 mL per gallon doing bubbles first and then goats and the other girl next to it👍 8/5 7:10 AM I’ve been doing this since five and I can’t believe how high my EC was. It was off the chart like 6000 7000 so I had to do the flush. I’m never really bothered to do this before. I’m sure it’s gonna be a lot better. One of my last grows. The leaves were so full of garbage. Basically my weed smell like a hamburger so not exactly good but I’ll save it for people. I don’t like👍. Sometimes it doesn’t remember a whole paragraph. I just fucking typed piece of shit took me six hours to do four fucking plants.🤣💥💥💥 8/6 408am. The colas on the oldest of the 3 are AMAZING!!!! they are all small but MIGHTY!! 2 cola grows in 1 gallon seem to be about right. I will probably get 4oz dry from EACH!! That is really acceptable!!! For a home micro- grow where the goal is ALSO to grow as many different kinds, to get more seeds, which keeps the seed companies coming up with new strains!!!! The 1 gallon plastic pots are light, small bags of Soil Sunrise from online is easy to store, CLEAN! the bags of dirt it comes in are strong, and easy to wipe up when done. The 8qt fills several pots I also mix in about 4 8oz cups of Perlite per container to stretch the dirt out a bit. Soil Sunrise delivered by amazon is the only dirt that did NOT have bugs...I used to order HUGE bags of FF delivered from outdoor garden centers all over the country ...the bug infested HORROR, never again!!! 8/6 418am Also my body is starting to fail, I can feel it. If there is any discomfort there will be no more updates. thats life. doesnt it go by in a blink? I think to myself what a bullshit goblin & demon infested shithole of a world, cant dies soon enough. And death to the shitters of 1978!!!😡 Did you ever hear about the Tragedy of Darth Arnie and Christine? He's more Chrysler 1958 Plymouth Fury than man now...maybe I got the movies mixed up again....idk....
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Hi guys, What's up? Welcome back to Queen Peaky's Flower Gardens We meet together again to wrap up another diary on these magnificent autoflowers We started working on the roots by rinsing them with only pH balanced water and a few little girls and Ready to be dried, preparing it for a perpetually dry trimming
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@TST1313
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vor ca 1 Woche in die Blüte geschickt 😜, sie wächst jetzt 4 cm am Tag .so einen Stretch habe ich noch nie gesehen 😊 Ich merke aber Zelt sowie LED kommen an ihre Grenzen,und Durst hat Sie. Ich hoffe das wird mehr als 20 g
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Tropical Storm Ian in the vicinity. Thankfully not much rain or wind so far. One midweek feed. Pots will need a while to dry out from all this rain. Hopefully no insect or mould/mildew damage.
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Day 8 - so I’m into my 2nd week, no problems to report. Will be purchasing a 300w LED in the next couple of weeks for flowering. Growth has remained steady, gave each a small amount of nutes today, about 1ml per 500ml or so, not going to feed much just yet as these babies have only just started. I may upload a video unboxing the LED growlight and showing my setup, will also be purchasing a ph / moist monitor. ✌️🏻 Day 12 - tried hanging pots using bungee cords but it wasn’t worth the hassle, it made the setup a little more fragile. Happy with the overall setup now, plants at a good distance from CFL. I have ordered Advanced Nutrients Grow Micro Bloom pH Perfect and CalMag, they should arrive tomorrow so I am excited! 😍 ordering 300w LED next week ✌️🏻 Day 13 - nutrients have arrived, super excited!! Day 14 - plants responding well to the nutrients! Week 2 is over, plants looking healthy, roll on week 3! :)
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Sending them into flower, let’s see what they can do! Plant in the back looking like a absolute keeper. Greenhouse plants doing insanely good.
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Very disappointed, thrips stunted growth and I’m debating weather to pull them out and start again.
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@Budcrack
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New update for week 12, concluding week 8 of flowering: Hi(gh) Folks! Thanks everyone for your input on my second grow question. I’m going for HighTV’s answer, the SOG with 9x4 main buds. Very nice to get everyone’s input on this, appreciate it! So another week done! They got their last nutrients Tuesday and on Thursday the 5 early ladies from Hempire got their first round of plain acidulated water. I flushed them a bit on Friday and Saturday to. Now they can dry out for a couple of days. I will flush them for the upcoming week and let them dry out before harvest next weekend. Im counting on them to swell up even further during this week. As for the rest of the 4 plants from Hempire, 4 from Royal Queen Seeds and 3 from Hy-Seeds, I will treat them as if this is another week 8, and they will get another dose of Flowering nutrients and PK. Then next week I will start to flush them also. I will have 2 full weeks to flush and let them dry out until my planned harvest on Saturday 5 January. I’m not even sure that will be early enough for the 4 RQS’s since they look like they have even more bud-growing to do, before they can start swelling! I will keep an eye on that. The 5 tall ladies, 2 from Hempire and 3 from Hy-Seeds show the nice thick Kushy buds i’m craving for, can’t wait to see the becoming nice and heavy! On the photos you see the slight diverence between the pheno’s, the left 2 plants grew the popcorn-buds on a stem, and the right ones have nice thick popcornbuds against the stem’s. The other to remaining Hempire plants also show these, apart from the early ladies offcourse. The early birds show a little stretching buds and nice purple colours. So next week will see the early ladies harvested, I hope? Look out for my next update and don’t forget to like! Thanks and see you!
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@Zuppler
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Week 9 - Fourth Week of Flower The Donutz gang is hitting its stride as the fourth week of flower unfolds. Trichomes are developing beautifully, and the plants are entering full production mode. A few challenges cropped up this week, but quick thinking and some DIY ingenuity kept everything on track. Key Updates: Trichome Progress: The resin glands are popping off, with a frosty layer forming across the developing buds. The plants are starting to show their true potential, and the tent is starting to smell. New Fan Installation: The old ventilator tapped out this week, so a replacement was installed to maintain proper airflow. This ensures the plants stay cool and prevents any issues with humidity or stagnant air. Lamp Adjustment: The front-left plant shot up too close to the light, so I had to get creative. I built a DIY solution to raise the lamp higher, ensuring even coverage and preventing light stress. Accident Recovery: During the light adjustment, I initially tried securing the front-left plant with a rubber band. Concerned it might melt, I removed it, but in the process, the main stem got damaged. Thankfully, the plant is a fighter. The main cola is now growing sideways but remains fully healthy and strong. This unexpected twist has added some character to the tent, and the plant is bouncing back beautifully. Observations: Despite the challenges, all plants are thriving, with strong growth and healthy bud development. The sideways-growing cola on the front-left plant is a unique highlight, showing the resilience of the Donutz genetics. Next Steps: Keep monitoring airflow and light height to avoid any further issues. Continue with the nutrient schedule and reverse osmosis (RO) watering to maintain stability. Watch the trichomes closely as they continue to mature, signaling the start of the final phases of flower. The Florida Gang grind is real, and the Donutz are proving their worth week after week. This tent is shaping up to be a legendary grow!
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Almost there. Took a look at her close up and most trichomes are cloudy. Added Overdrive this week to start that finishing process. Each branch has a really nice sized cola on top. Powdery mildew is practically dead in its tracks thankfully, meaning its not spreading. A bit pops up here and there, a quick but precisely guided spray with Safers Brand 3-1 and we are good. You can see it in the overshot on some leaves. This was before treatment. As far as the nitrogen toxicity, ive cut out the ph perfect line for her, minus 1ml of micro...i may even cut that. Notice how dark and thick the leaves are. I have a feeling that if I cut all nutrients now she would finish fine. Tell me what you think!
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@Salokin
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The week went uneventful the plant is doing what it's supposed to be doing. The wifey is doing a great job in taking care of the plant while im travelling. Introduced Hess's PK 13/14 from the last feeding. PPM remained flat at 900 and will now gradually increase the PK 13/14 over the next weeks. Looks pretty good from what I can tell by the pictures I received. Still a bit of tip burn so, will decrease the base nutrients a little as well over the next few weeks.
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@MnmlMe
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Obenrum fertig, untenrum nicht.
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@romi27
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Yellow climbed all the way up both plants. Been flushing for a while. Trichs seemed to be maturing very slow, since the sugar and fan leafs were already yellow and crispy. About to harvest even with only about 15% amber trichs. Should reach normal maturity while drying and curing. I'm going to give them a full 48 hours of darkness before the chop.
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Day 1. The cuttings after being rooted in the special tray were transplanted into small jars and allowed to acclimatize in the appropriate boxes. After a few days we transplanted them into 18 L pots filled with plagron growmix, a prefertilized substrate, and then they were placed inside our cultivation box, the one in the photos. Being a prefertilized substrate we watered with only water with a pH of 6.5 until the water ran out into the saucers. As the 18 L pots are very large, no more water was needed for the first 5 days. DAY4. The plants were topped.
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@Grey_Wolf
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Fast Buds Mexican Airlines 5 weeks into Flowering completed 18th Jan 2020 Well she's starting to fill out a lot more now and is getting fairly sticky and stinky. Probably another two weeks or so left before it's ready but no rush. The weathers turned a little and is threatening to rain so I'm juggling between moving them into the sunlight then back under cover when it looks a bit clouded and ominous. Thankyou for looking at my latest update 👍
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🍼Greenhouse Feeding BioGrow & BioBloom ⛺️MARSHYDRO The ⛺️ has a small door 🚪 on the sides which is useful for mid section groom room work. 🤩 ☀️ by VIPARSPECTRA (models: P2000 & XS 2000) 🌱 DUTCH HEADSHOP SEEDS: www.dutch-headshop.eu www.dutch-headshop.nl ONE STOP SHOP . 100% germination success on first try! with HUGE seed selection! . Very friendly customer service . Best bio-seed packaging . Sells other products @ best prices: . Nutrients . Vaporizers . Smoking accessories (grinders, cones) . CBD Tinctures . Resin Extracts . Boveda humidity packs . Ziplock bags . Other health supplements such as: . Lion’s Mane Organic Capsules . Hemp Seed coffee
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This week was a blessing... Everything went smoothly, except..I had my grow light a little too close to her... **Tips Burnt abit** But, I corrected the mistake that should not have happened in the first place if I payed attention to the setup 🤣😫.. Other than that she is doing quite well as you can see 👀 😉