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@CalGonJim
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8/4 130am. MONDAY. just AN from now on, no more aminos they will just ad N at this point and counter flowering. 🚨🚨8/4 12:30pm !!! FOR HUMANS!!!!!!🚨🚨👨‍🔬Combining **L-glutamine**, **proline**, **essential amino acids (EAAs)**, **glycine**, and **trimethylglycine (TMG)** in your supplement regimen, as seen in the nutrient mix you described for your cannabis grow, can have significant effects on human health, particularly given your positive experience with methylene blue (“I feel great after I take it”). Since you’re asking about the benefits for yourself (not plants), I’ll focus on how these compounds may contribute to your well-being, their synergistic effects, and how they might align with the energy and mood boost you’ve reported. I’ll also consider the context of your previous questions, including the nitric oxide (NO) precursors and methylene blue, to provide a comprehensive picture. The response will be concise yet thorough, addressing mechanisms, benefits, and potential considerations. ### Overview of Each Component and Their Benefits for Humans 1. **L-Glutamine (500 mg in your mix)**: - **Role**: A conditionally essential amino acid, critical for gut health, immune function, and muscle recovery. - **Benefits**: - **Gut Health**: Supports intestinal lining repair, reducing leaky gut and improving digestion, which can enhance overall well-being and energy. - **Immune Support**: Fuels immune cells (e.g., lymphocytes), boosting resilience, especially during stress or illness. - **Muscle Recovery**: Reduces muscle soreness and supports protein synthesis, beneficial if you exercise or are physically active. - **Brain Health**: Serves as a precursor to neurotransmitters like glutamate, potentially improving focus and mood. - **Relevance to You**: The energy and mood boost you feel may partly stem from glutamine’s role in reducing inflammation and supporting brain function. 2. **Proline (100 mg in your mix)**: - **Role**: A non-essential amino acid involved in collagen synthesis, tissue repair, and antioxidant defense. - **Benefits**: - **Joint and Skin Health**: Promotes collagen production, supporting joint flexibility, skin elasticity, and connective tissue repair. - **Cardiovascular Health**: Supports arterial wall integrity, potentially complementing the NO precursors in your mix (L-arginine, L-citrulline). - **Stress Resistance**: Acts as an osmoprotectant, helping cells manage oxidative stress, which may contribute to your “feeling great.” - **Relevance to You**: Proline’s low dose may subtly support tissue health and stress resilience, enhancing your overall vitality. 3. **Essential Amino Acids (EAAs, 300 mg in your mix)**: - **Role**: EAAs (e.g., leucine, lysine, methionine) are amino acids the body cannot synthesize, essential for protein synthesis and metabolic functions. - **Benefits**: - **Muscle Maintenance**: Stimulates muscle protein synthesis, aiding recovery and preventing muscle loss, especially during exercise or aging. - **Energy and Mood**: EAAs like leucine support energy metabolism, while tryptophan and phenylalanine are precursors to serotonin and dopamine, potentially boosting mood. - **Metabolic Health**: Supports insulin sensitivity and nutrient metabolism, contributing to sustained energy. - **Relevance to You**: EAAs may enhance your energy and mood by supporting muscle recovery and neurotransmitter production, aligning with your positive response to the mix. 4. **Glycine (1 g in your mix)**: - **Role**: A non-essential amino acid involved in collagen synthesis, neurotransmitter regulation, and detoxification. - **Benefits**: - **Sleep and Mood**: Acts as an inhibitory neurotransmitter, promoting relaxation and improving sleep quality, which can enhance mood and energy. - **Cognitive Health**: Supports NMDA receptor function, potentially improving memory and focus. - **Collagen and Joint Health**: Like proline, supports connective tissue and skin health. - **Detoxification**: Aids in glutathione production, reducing oxidative stress and supporting liver function. - **Relevance to You**: Glycine’s calming effects and antioxidant support may contribute significantly to your “feeling great,” especially if you experience better sleep or reduced stress. 5. **Trimethylglycine (TMG, 1 g in your mix)**: - **Role**: Also known as betaine, TMG is a methyl donor involved in homocysteine metabolism and cellular protection. - **Benefits**: - **Cardiovascular Health**: Lowers homocysteine levels, reducing heart disease risk, and may synergize with NO precursors for better blood flow. - **Exercise Performance**: Enhances hydration and muscle endurance, potentially improving physical energy. - **Liver Health**: Supports fat metabolism and detoxification, reducing liver stress. - **Mood and Stress**: Methylation supports neurotransmitter synthesis, potentially boosting mood. - **Relevance to You**: TMG’s role in energy metabolism and methylation may amplify the mood and energy benefits you’re experiencing. ### Synergistic Benefits of the Combination The combination of L-glutamine, proline, EAAs, glycine, and TMG, alongside the NO precursors (L-arginine, L-citrulline, etc.) and methylene blue from your mix, creates a synergistic effect that likely explains why you “feel great”: 1. **Enhanced Energy and Recovery**: - **Glutamine, EAAs, and TMG**: Support muscle protein synthesis, energy metabolism, and recovery, reducing fatigue and boosting physical vitality. Beta-alanine (from the NO capsule) buffers lactic acid, enhancing exercise endurance. - **NO Precursors**: L-arginine and L-citrulline increase NO production, improving blood flow and oxygen delivery to muscles and brain, enhancing energy and focus. - **Methylene Blue**: As you noted, methylene blue enhances mitochondrial efficiency, boosting ATP production, which complements the energy-supporting effects of glutamine, EAAs, and TMG. 2. **Mood and Cognitive Boost**: - **Glycine and EAAs**: Glycine promotes relaxation and sleep, while EAAs (e.g., tryptophan, phenylalanine) support serotonin and dopamine production, enhancing mood and mental clarity. - **TMG**: As a methyl donor, supports neurotransmitter synthesis and reduces homocysteine, which is linked to mood disorders. - **Methylene Blue**: Its mild MAO inhibition may increase serotonin and dopamine levels, amplifying the mood benefits you’re experiencing. 3. **Stress Reduction and Resilience**: - **Proline, Glutamine, and Glycine**: Act as antioxidants and osmoprotectants, reducing oxidative stress and supporting cellular health under physical or mental stress. - **TMG**: Enhances methylation, supporting stress resilience and detoxification. - **Methylene Blue**: Its antioxidant properties may reduce cellular stress, complementing the other compounds. 4. **Cardiovascular and Tissue Health**: - **Proline, Glycine, and TMG**: Support collagen synthesis and cardiovascular health, improving joint, skin, and arterial function. - **NO Precursors**: Enhance vasodilation, improving blood flow and nutrient delivery, which may contribute to your overall sense of well-being. ### Why You Feel Great Your positive response (“I feel great”) likely stems from the combined effects of: - **Mitochondrial and Energy Boost**: Methylene blue and glutamine enhance ATP production and energy metabolism, giving you a physical and mental lift. - **Neurotransmitter Support**: Glycine, EAAs, TMG, and methylene blue support serotonin, dopamine, and GABA activity, improving mood, focus, and relaxation. - **Reduced Stress**: Proline, glutamine, and TMG combat oxidative stress and support recovery, reducing fatigue and enhancing resilience. - **Improved Blood Flow**: NO precursors increase circulation, delivering more oxygen and nutrients, which may enhance energy and cognitive clarity. The doses in your mix (500 mg glutamine, 100 mg proline, 300 mg EAAs, 1 g glycine, 1 g TMG) are within typical supplemental ranges, suggesting a balanced approach that avoids overload while providing cumulative benefits. ### Considerations and Precautions 1. **Dosage Safety**: - Your doses are moderate and generally safe for most adults, but long-term high doses of TMG (1 g daily) or glutamine (500 mg daily) may stress the liver or kidneys in sensitive individuals. Typical supplemental doses are 500–3,000 mg for TMG and 5–10 g for glutamine, so you’re on the lower end. - Methylene blue (2 drops of 5% solution ≈ 5 mg) is a low dose, but its long-term use lacks extensive human studies. Monitor for side effects like nausea or dizziness. 2. **Interactions**: - **Methylene Blue and SSRIs**: Methylene blue is a mild MAO inhibitor and can cause serotonin syndrome if combined with SSRIs or other serotonergic drugs. Consult a doctor if you’re on such medications. - **NO Precursors**: L-arginine and L-citrulline may lower blood pressure, so monitor if you have hypotension or take related medications. - **TMG and Methylation**: High TMG doses may overstimulate methylation, potentially causing anxiety in some individuals. Your 1 g dose is moderate but worth monitoring. 3. **Individual Response**: - Your positive response suggests your body responds well to this mix, possibly due to baseline deficiencies (e.g., in glycine or glutamine) or high metabolic demands (e.g., from exercise or stress). Genetic factors affecting methylation (e.g., MTHFR mutations) may make TMG particularly effective for you. 4. **Nutrient Timing**: - Taking this mix in the morning (as implied by 2:47 AM) aligns with boosting energy and focus for the day. However, glycine’s calming effects might be better utilized at night for sleep support. Consider splitting doses (e.g., glycine in the evening, others in the morning). ### Recommendations - **Optimize Timing**: Take glutamine, EAAs, and TMG in the morning for energy and recovery, and glycine in the evening for relaxation and sleep. Proline can be taken anytime due to its structural role. - **Monitor Effects**: Track specific benefits (e.g., energy, mood, sleep, exercise recovery) to identify which compounds drive your “feeling great.” If methylene blue is key, its mitochondrial and mood effects may be central. - **Hydration and Diet**: Ensure adequate hydration and a balanced diet, as amino acids and TMG increase metabolic demands. Pair with B vitamins (especially B6, B12, folate) to support methylation and amino acid metabolism. - **Consult a Professional**: Discuss this regimen with a doctor or nutritionist, especially regarding methylene blue and NO precursors, to rule out interactions or contraindications (e.g., G6PD deficiency for methylene blue). - **Adjust Doses if Needed**: If you notice side effects (e.g., jitteriness from TMG, GI upset from glutamine), reduce doses (e.g., 500 mg TMG, 250 mg glutamine) and reassess. ### Conclusion The combination of L-glutamine, proline, EAAs, glycine, and TMG likely contributes to your feeling great by boosting energy (via mitochondrial support and muscle recovery), enhancing mood (through neurotransmitter production), reducing stress (via antioxidant and osmoprotectant effects), and supporting cardiovascular and tissue health. Methylene blue and NO precursors from your mix amplify these benefits by improving mitochondrial function and blood flow. Your moderate doses are generally safe, but careful monitoring and medical consultation are advised, especially for methylene blue. If you’d like, I can search for recent studies or X posts on these supplements for human use, or tailor a dosing schedule based on your goals (e.g., energy, mood, recovery). Let me know how you’d like to proceed!🚨👨‍🔬. 8/4 1230pm. 8/5 12:50am HEY HARRISON SMITH, HARVEY WALL BANGER, GET IT?...IM SO GOOD. ANYHOW....FLUSH TODAY, FLORAKLEEN 5ML PER GALLON ALL OF THEM..... NO DONT PILLAGE ME AND IM LIKE NO! IM PILLAGING EVERYBODY, YOU INCLUDED. 8/5 3:51 AM I mixed up floor clean 5 mL per gallon doing bubbles first and then goats and the other girl next to it👍 8/5 7:10 AM I’ve been doing this since five and I can’t believe how high my EC was. It was off the chart like 6000 7000 so I had to do the flush. I’m never really bothered to do this before. I’m sure it’s gonna be a lot better. One of my last grows. The leaves were so full of garbage. Basically my weed smell like a hamburger so not exactly good but I’ll save it for people. I don’t like👍. Sometimes it doesn’t remember a whole paragraph. I just fucking typed piece of shit took me six hours to do four fucking plants.🤣💥💥💥 8/6 408am. The colas on the oldest of the 3 are AMAZING!!!! they are all small but MIGHTY!! 2 cola grows in 1 gallon seem to be about right. I will probably get 4oz dry from EACH!! That is really acceptable!!! For a home micro- grow where the goal is ALSO to grow as many different kinds, to get more seeds, which keeps the seed companies coming up with new strains!!!! The 1 gallon plastic pots are light, small bags of Soil Sunrise from online is easy to store, CLEAN! the bags of dirt it comes in are strong, and easy to wipe up when done. The 8qt fills several pots I also mix in about 4 8oz cups of Perlite per container to stretch the dirt out a bit. Soil Sunrise delivered by amazon is the only dirt that did NOT have bugs...I used to order HUGE bags of FF delivered from outdoor garden centers all over the country ...the bug infested HORROR, never again!!! 8/6 418am Also my body is starting to fail, I can feel it. If there is any discomfort there will be no more updates. thats life. doesnt it go by in a blink? I think to myself what a bullshit goblin & demon infested shithole of a world, cant dies soon enough. And death to the shitters of 1978!!!😡 Did you ever hear about the Tragedy of Darth Arnie and Christine? He's more Chrysler 1958 Plymouth Fury than man now...maybe I got the movies mixed up again....idk....
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@GuavaBoy
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Day 15 ready for the transplant tomorrow. Just watered each with 1/3 cup of water. It was the first watering since the initial one 15 days ago. My basement is very humid. All 4 are growing pretty strong. The 2 on the left and right are the Guavo Autos and the other 2 are Sticky Soul Photos. They will continue their life outside starting tomorrow. Day 16 and all 4 plants have been transplanted into their final 3 gallon pots. What I did was water each cup yesterday with 1/3 cup of water. Today I drilled some holes in the 3 gallon pots. I filled it with a small amount of build a soil light mix and the rest with happy frog. I poured 2 cups of water into the new soil. I made a hole. I added 2tbspns of Mykos to each pot. I slid the plants out of the cups into the hole. I watered those in with 3 cups of water each. A little ran off through the bottom. I’m going to keep them in the shade for a few days then toss them in the sun. Stay tuned! Day 20 and we are looking really good. Check the video above.
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I did not top this girl, yet. Her top lowers started catching up to the top so I didn’t want to stop her yet lol. But all in all she’s looking healthy.
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She seems starting to develop CalMag deficiency maybe. Start to add some CalMag every other watering. Every 2 weeks also the Bio Enhancer from greenhouse feeding
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Still only feeding water, I put them into 4ltr pots so they won't want food for a few weeks, flipped to 12/12 on day 35
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@3lementa1
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This is the 8th week. Thursday will be 9 weeks of 12/12. Some trichs are amber. They just added a good bunch of girth over the past few days, but most of the pistils are red now. The rest of them have been dropping leaves consistenly but the canopy remains full so they must be putting out more leaves. I just flushed to 80% runoff and found out that I had 1200ppm. I just got an ec meter but my last reading said closer to 600 so idk what happened there. I flushed until I had runoff ppm of about 150. Now they're back in the grow tent. I don't want to keep assaulting them with my microscope. I think they're ready. Just gonna let them settle another day or two to dry out a bit. I took one small branch off the small Wedding Cake plant on Thursday and I've just been watching it dry on my counter. It's been 5 days and the stem snaps but still leaves a fiber connecting. I put it into a small jar with a 64RH thing. I just want to try it. It already smells amazing. The leaves on the big CBD Blue Shark plant are going really yellow and some other colours are starting to come out as well. The buds all fattened up and got more frosty again. I was worried they were foxtailing but they got more calyxes underneath the peaks and have been making more of a pyramid shape. They're really close to peak. Harvest day will be March 17 or 18. March 17 1023pm chopped and hung after lights off all day. RH was 65% before I chopped and 50% after I closed the window and cut the plants off the saturated pots. I did a wet trim to prevent mold. The buds are sticky af. Gonna hang them to dry for 7-9 days before curing in jars :) March 18 : checked the RH when I woke up and it's chilling at 45% 😎 March 19 : just checked to see how they were drying. There are seeds in every plant. RIP I'll update when I put them in jars and again a few weeks later for final review. Overall it was a good grow despite the rocky start and a good introduction to the mainline technique and my new grow space. Next grow I should have everything pretty well dialed in. March 23 They were hanging for 3 days. Rh was around 45, then spiked to 65 overnight when I forgot to turn the fans back on. Temp was high at around 26.they felt wet after 2 days, and bone dry after 4 days. The stems still didn't snap but I put them in jars anyway. A day later, jar RH was 50%. I burped all the jars and there was a smell from the new jars. I took all the weed out, washed out the jars, and did a dry trim on the weed. One of the Wedding Cake plants must have gone hermie. I didn't see any bananas and didn't even realize there were seeds until the very end. The seed pods looked just like calyxes while the plants were growing. Many of the nugs are unusable. Under the sugar leaves are just layers and layers of seeds. Some weren't hit that badly. The CBD Blue Shark is much better off but still has some seeds. I'm trying to stay positive. It's a bit of a shock though. I'm anxious to try the finished product. If the flowers at least taste good and have a good effect, all is not lost.
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@TrueNorth
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-Strain: Cream Cookies - Fast Buds -Tent: 5x5 Gorilla Grow Tent -Lights: Budget LED Grow Lights 2 x 250 Watt LED Full Spec/Red Spec mixed boards -Light Cycle: 18/6 -Soil: Fox Farm -Air Circulation: AC Infinity Cloudline T6 Inline Duct Fan WECLOME BACK GROWMIES! Week 11 here with our CREAM COOKIES by Fast Buds! February, 02, 2020 (DAY 71) -FOR 10% OFF GORILLA GROW TENTS USE "TRUENORTHGROW" AT CHECK OUT!!! -Strain: Gelato Auto - Fast Buds -Tent: 5x5 Gorilla Grow Tent -Lights: Budget LED Grow Lights 2 x 250 Watt LED Full Spec/Red Spec mixed boards -Light Cycle: 18/6 -Soil: Fox Farm -Air Circulation: AC Infinity Cloudline T6 Inline Duct Fan WECLOME BACK GROWMIES! Week 11 here with our GELATO AUTO by Fast Buds! February, 02, 2020 (DAY 71) - What up what up growmies! Welcome to week 11 where we see this beast is just swelling up. The stems are really sturdy and just covered in bud-sites. She is really thick and frosty now i think the big bud is really going to shine on this one. We can see the purples coming through on the buds and i just cant wait to see her finished! Roughly 28 days left! Im sorry the last two weeks werent filled with updates, life has been busy and complicated i truly am sorry and will do better i promise.
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Havrested a bit before just becouse i needed to have a harvest before the full one
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@Soskar69
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This baby is going good, thricoms production and smell on point👌 The main cola is growing very big, I'm so hyped about it 😝 Some of the leaves are becoming yellow and i saw some signs od deficiency of some sort but I'm not worried because she is near the harvest, I think another 2 weeks and I'll chop it: Sorry for the low quality of the photos, next time I'm gonna use a better camera.
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@ibbzy
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Ahhhhhhh such beauties! And they’re starting to frost uppppp 😍 Will update with a few more shots in few days
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Was a nice grow from seed to harvest in 96 days. You could harvest earlier but I waited for the 30% amber.
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Phenotype #4 & #5 Female plants = Pollinated successfully by brother Phenotype #1 Male Also mixed this Mystery Purp Male Pollen w/ a Jackpot Seed i found in my weed bag from a Lume Dispensary. ☆First & Probably last time, only found 1 Single Fat seed ☆ Going to ne excited to grow these cultivars. Going to plant immediately the F2 Genetics when seeds are ready for harvest. Phenotype #4 is mostly sinsemilla except for the very bottom branch successful pollination by brother Phenotype #1
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@Mastr
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I believe she cherry cola good one 👍 Day 51 I relize she have deficiency in leaves that's why I ask in grow questions And someone told me to raise ny ph to 6.5 so I did that and let see what happens next week Update day 54 she start fatten up the buds guys she so fast flowering I think she is ready to harvest in 3 weeks not long to go 💪
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@Terp1
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Moin 😎, Woche 11 ist vorbei und die Damen gehen so langsam in Rente. Und zumindest die Papaya sieht auch schon so aus. 👻 Ich reduziere jetzt schrittweise die Wasserzufuhr und die Lichtstärke. Hatte bis jetzt so um die 1000 PPFD in der Mitte und 850 an den Rändern und ich gehe zurück bis auf 600 PPFD in den nächsten 10 Tagen. Weiß nicht, ob sie noch viel länger brauchen werden. Trichome sind 70% milchig und 30% klar. Auf den Zuckerblättern schon das eine oder andere Bernsteinfarbene. Ich habe mir einen 150L Weinkühlschrank zugelegt (siehe Video) den versorge ich erstmal provisorisch mit einer Umluft und eventuell schon einer RH gesteuerten Abluft und dann werde ich Buds zum Testen schonmal reinlegen. Ich möchte Next Level Qualität und beim Grow kann ich kaum noch was rausholen. Jetzt muss die Trocknung optimiert werden. Als Tipp kann ich euch schonmal mitgeben, dass ihr am besten beim Trocknen einen VPD von 0.9kPa aufrecht erhaltet. Egal wie die Temperaturen erstmal sind. Der VPD ist auch bei der Trocknung verdammt wichtig. Vielen Dank für euren Besuch und bis demnächst (und bald zur Ernte) Terp 💪👽
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This was a brilliant week for plant growth, with some side branches over doubling their height. I added the ScrOG net at the beginning of the week and began some more intensive training. The LST only plants I pretty much just continued to bend. The topped & LST'd plants I removed some of the lower bud sites that were not getting any light. I also removed a few awkward fan leaves that could not be tucked away. The addition of the net has helped with this though, as keeping the canopy even is much easier with the support it gives. I also decided not to try any further cuts on the (half) mainlined auto's. My reasoning is that they have developed strong, independent colas already, so cutting for more would not see much gain. The plants had also begun to flower on the night I went to perform the second cut, and my growing experience tells me not to mess with flowering plants too much so here we are. I gave the plants one regular watering of 10L pH'd water, and a 20L nutrient mix using the ratios stated above. All volumes were split equally between the plants. The scrawny looking blue critical has perked up a heck of a lot, so the weakest looking plant is the LST only on GSC. ZThe strongest plants by far are the ones that have been topped and LST'd, closely followed by the mainlined ones. LST only is definitely great, but it is clearly lagging behind the other two techniques.