Best weed strains that may help inflammation

Many people turn to cannabis as a natural solution for managing inflammation. While it’s not a cure for inflammation, there’s a huge body of research to support cannabinoids like THC and CBD contain anti-inflammatory properties. While CBD and THC are both promising for inflammation support, they’re said to work better together when it comes to managing inflammation. We’ve created a list of the meat weed strains that may help with inflammation, each with their own unique effects and distinctive cannabinoid profile. Some are sativa leaning and offer bright daytime high with soothing physical effects, while others are more indica dominant with heavy, relaxing effects said to help with sleep. You’ll also find a few strains that meet in the middle, offering balanced hybrid effects that are both energizing and relaxing. 

If you’re interested in the best strains for inflammation or managing symptoms of inflammatory conditions, such as gastrointestinal disorders, asthma, arthritis, Chron’s disease, and more, keep reading to learn more about the best strains that may help.  

Harlequin

Harlequin is a gorgeous sativa-dominant hybrid that’s more commonly used medically than recreationally thanks to its low THC / high CBD concentration. With 12% THC and 9% CBD, this Columbian Gold, Thai, and Swiss landrace sativa cross comes close to the 1:1 “golden ratio” that studies show may enhance weed’s therapeutic effects. Harlequin has a fruity, earthy flavor that blends mango and citrus with woody and spicy herbal notes — with enough THC that will produce slightly psychoactive cerebral effects that are more uplifting and focused than they are intoxicating. The body high is calm and relaxing without being at all sedating. Medical cannabis patients widely report Harlequin is one of the best strains for inflammation, anxiety, stress, and depression.  

Wedding Crasher

Wedding Crasher is a slightly indica leaning hybrid with 23% THC and a gently, relaxing head and body high commonly used to soothe inflammation and ease symptoms of depression and stress. It’s one of the best strains that may help with inflammation for consumers looking for a well-balanced high that isn’t sedating or overly stimulating. This Wedding Cake and Purple Punch cross has a lovely vanilla and grape flavor with a subtle spicy herbal finish, and delivers a smooth euphoric and focused high that’s simultaneously soothing and relaxing. 

Lemon Tree 

Lemon Tree, also known as Lemon Tree Kush is a lovely balanced hybrid beloved by rec and medical consumers alike. This Lemon Skunk and Sour Diesel cross has a strong skunky lemon and diesel-fueled taste you’d expect from its genetic line, and is favored by MMJ patients for powerful therapeutic potential said to support inflammation, pain, and depression. With 23% THC, it produces notably potent effects, delivering an uplifting and happy head high that leaves consumers contently relaxed. It’s one of the best strains for inflammation with powerful, evenly balanced effects, making it ideal for soothing support any time of day. 

Chronic

Chronic is a heavy leaning indica hybrid considered one of the best strains for inflammation thanks to its blended concentration of around 22% THC and 5% CBD. With research that supports THC + CBD blends produce an anti-inflammatory effect, this Northern Lights, Skunk #1, and AK-47 triple cross is cherished by medical cannabis patients for inflammation support. Its quick-hitting cerebral euphoria delivers a happy, creative head high that boosts mood and makes you giggly and talkative — which may relieve stress, anxiety, and depression — while its relaxing body high will eventually have you contently couch-locked. Its flowery flavor blends sweet honey with notes of strawberry and other berries for a delightful sensory experience and relaxed, happy high that may help regulate the inflammatory response. 

NYC Diesel

NYC Diesel is a sativa leaning hybrid strain created in 1997 that’s gone on to win almost a dozen awards since — including three gold medals at the High Times Cannabis Cup. This East Coast fan favorite is reported to help soothe inflammation, stress, and depression — delivering a motivating and happy high that’s also relaxing without sedation that makes it an ideal daytime strain for managing inflammation and boosting mood. It’s also known for its appetite stimulating properties, which is another common medical use for this pungent diesel and chemical tasting bud that puts off a bright lime and grapefruit aroma on the exhale. 

Critical Mass

Critical Mass is an indica-dominant hybrid created from an iconic lineage that contributed to its wonderfully euphoric and relaxing effects. This Skunk 1 and Afghani cross got its name from the heavy weight of the dense buds it produces late in flower that smoke smooth with a sweet earthy flavor that finishes with a skunky citrus aftertaste. It delivers a unique high that starts off with a blissfully happy, relaxed high with a subtle boost of energy that still lets you get things done. This slightly uplifting head high soon becomes a deeply sedating and sleepy experience that’s perfect for getting a good night’s rest. Reported to support inflammation and inflammatory-related conditions, including multiple sclerosis, chronic pain, and anxiety, Critical Mass is one of the best strains for inflammation that’s ideal for early evening or nighttime use. 

Thai

If you’re interested in an energizing sativa known for powerful anti-inflammatory effects, Thai is a pure sativa landrace from the country it was named after. This coveted classic with a moderate 14% THC concentration is widely respected in the cannabis community as one of the most iconic strains of all time. Thai delivers an energizing and euphoric head high that will have you feeling focused and creative for hours. It’s an ideal daytime strain for soothing physical discomfort caused by inflammation, with mood-boosting effects said to support stress and depression.  

Ice

Ice is a balanced hybrid quadruple cross created from Northern Lights, Skunk 1, Afghani, and Shiva Skunk that medical patients commonly use to support inflammation, gastrointestinal disorders, and asthma flare-ups. It produces brilliant light lavender and soft green hued buds with a thick layer of frosty white trichomes, giving it an appearance that reflects its name. Ice inherited the pungent diesel and earthy chemical-like flavor with pepper notes blended with menthol, pine, and citrus you’d expect from its parents. It contains around 18%, producing an onset of powerful cerebral euphoria that becomes a happy and giggly high, before its relaxing indica roots take over and you find yourself hungry and hazy with a sedating high that settles in and makes you sleepy. Aside from its anti-inflammatory potential, Ice is said to help relieve insomnia, stress, and symptoms of depression. 

Trophy Wife

Trophy Wife is a beloved medical cannabis strain with a low THC (10%) and high CBD (5%) concentration, giving it that 1:1 “golden ratio” of cannabinoids said to enhance the potential benefits of cannabis. Speaking of benefits, this Cherry Wine and The Wife cross is reported to be one of the best strains for inflammation support, relieving inflammatory related conditions such as arthritis and mood disorders like anxiety and depression. It has a chemical and earthy, citrus-forward flavor and delivers a super chill head and body high with long-lasting effects. Physically relaxing and soothing with subtle euphoric cerebral effects, Trophy Wife produces a soft, happy high with effects that are said to soothe the inflammatory process. It’s also highly sought-out by MMJ patients with seizures and epilepsy.  

Midnight Runtz

Midnight Runtz is a gorgeous indica-dominant hybrid with powerfully relaxing head and body high thanks to its 25% THC and 8% CBD content. This Runtz and Funky Charms cross produces deep purple-hued buds covered in a thick coat of frosty trichomes with a sweet fruity flavor that tastes like blueberry and citrus candy. It delivers slow physical and cerebral effects that slowly engulf the body in a soothing euphoric relaxation with strong sedative-like effects known to induce a super sleepy state — making Midnight Runtz best for evening use and ideal for insomnia. Medical patients also report its one of the best strains for inflammation, soothing inflammatory related conditions like chronic pain, migraines, and gastrointestinal disorders such as irritable bowel syndrome.  

Cannabis is believed to help with inflammation because of its influence on the body’s endocannabinoid system (ECS), which evidence shows helps regulate the immune response, which helps to reduce inflammation and soothe inflammatory discomfort.