Cannabis has been used for nausea for hundreds, if not thousands of years, with the first recorded use of weed for medical purposes dating back to 2737 BCE in China. Be it a one-time occurrence or a symptom of chemotherapy, multiple sclerosis, or anorexia, among others, people experience relief when consuming cannabis. Furthermore, there are FDA-approved synthetic cannabinoids that are prescribed for nausea but can be expensive and hard to obtain. Additionally, they are only available in pill form, which can be problematic for patients who cannot swallow pills. This makes weed an ideal alternative thanks to its versatility as it can be consumed through joints, vapes, edibles, or oils. The main ingredient in cannabis that blocks sickness is THC, although new research suggests that CBD might help too. This means that certain strains are more likely to be effective against nausea than others. In the list below you’ll find strains that will help combat nausea, as reported by real-world users. Scroll through and find your best strain for nausea.
Best weed strains that may help nausea
Best weed strains that may help with nausea
People have been using cannabis to support nausea for decades — with its use to support nausea so common it’s become a qualifying condition in the majority of US medical cannabis states. Many of the estimated 3 million MMJ patients in the US use weed to relieve nausea, whether caused by occasional gastrointestinal discomfort, chemotherapy, or a chronic medical condition. Whether you’ve been consuming cannabis for years or are a new user looking to ease nausea, following you’ll find the best strains for nausea according to real-life users.
The best strains for nausea
Exploring the best strains for nausea starts right here. This carefully curated list of cultivars are all considered some of the best strains known to offer soothing digestive effects — including energizing sativas, relaxing indicas, and balanced hybrids that deliver the best of both worlds.
Dream Queen
Dream Queen is a sativa-dominant hybrid created by crossing the highly sought-after Space Queen with legendary Blue Dream. This earthy flavored fan favorite contains woody notes blended with subtle sage undertones and puts off a similar aroma with a deeper skunky scent. Known for delivering a highly cerebral head high that inspires a euphoric sense of happy, creative, social energy, this is one of the best strains for nausea thanks to the relaxed, hungry high that follows. Medical cannabis patients commonly use Dream Queen to support appetite loss, nausea, and fatigue.
Gary Poppins
Gary Poppins is one of the best weed strains that may help with nausea for anyone interested in a high-potency powerhouse. Packed with 27% THC, this balanced hybrid with a funky diesel and sour lemon taste delivers a potent uplifting head high pretty much instantly after exhaling that first zesty flavored hit. This powerful strain produces a soaring cerebral euphoria and super positive mindset with calming, relaxed physical effects that don’t make you lazy or sedated. The high THC in this strain makes it perfect for experienced consumers, while medical patients appreciate its efficacy in supporting nausea, appetite loss, and chronic pain.
Lemon Cream
Lemon Cream is a rare sativa hybrid with a deliciously sweet lemon flavor blended with vanilla and other citrus notes that delivers a rapid, long-lasting high. This is the best strain for nausea for anyone looking for daytime support for soothing an upset stomach. This Cookies and Cream and Lemon OG cross contains 24% THC, producing an energetic and uplifting high that will keep you going for hours — just be prepared for a big appetite boost thanks to the next-level munchies Lemon Cream produces. Medical patients report it helps soothe nausea, lack of appetite, fatigue, headaches, and migraines.
All Gas OG
All Gas OG is a sedating indica-dominant hybrid with around 22% THC that’s commonly used by medical cannabis patients to soothe nausea and treat appetite loss. If you’re seeking the best strain for nausea that will also help you sleep, consider All Gas OG your new go-to. This earthy, flowery flavored strain with distinct notes of diesel delivers a happy cerebral rush that boosts mood and positivity before a deeply relaxing and sedating body high sets in. Except to be sleepy and ravenously hungry after smoking this Venom OG and Humboldt cross. Aside from nausea and lack of appetite, it’s commonly used as a medical strain to alleviate insomnia, depression, and PMS symptoms.
Banana Cream Cake
If you’re interested in the best weed strains that may help with nausea and heavy indicas are your thing, Banana Cream Cake has you covered. This Cheesecake and Banana Kush cross with a sweet creamy and fruity flavor dominated by heavy notes of bananas and cream is cherished by medical cannabis patients for soothing digestive upset. It delivers energetic cerebral effects that hit fast, lifting you into a state of hazy happiness while a relaxing body high makes its way through the body, leaving you feeling lazy, hungry, and calmly content. It’s a common medical cannabis strain used for alleviating nausea and lack of appetite, as well as supporting depression and stress.
Snow White
Snow White is a stunning indica-dominant hybrid with a magnetic appeal to medical cannabis patients thanks to its superior efficacy in helping with nausea, lack of appetite, cramps, muscle spasms, and depression. Its gorgeous lavender-hued buds drenched in sparkling trichomes pack 24% THC and produce a sweet, woody and citrus flavor. This White Widow and Northern Lights cross delivers the coveted effects you’d expect from its classic parents — uplifting, euphoric, and giggly, before a lovely relaxing body high sets in, leaving you couch-locked and calmly sedated.
Blueberry Headband
Blueberry Headband is an indica-dominant hybrid that’s likely the best strain for nausea if you’re into cultivars with a sweet blueberry flavor. This Blueberry and Headband cross contains moderately low amounts of THC around 15%, making it one of the best weed strains that may help with nausea for low-tolerance canna consumers. It delivers a euphoric, uplifting head high before deep relaxation takes over the body — leaving you in a super serene state with a noticeable increase in hunger. Medically, Blueberry Headband is used to support nausea, appetite loss, anxiety, and stress.
Cherry OG
Cherry OG is a beautifully balanced hybrid that produces a perfect blend of uplifting cerebral euphoria soothing physical relaxation. This Cherry Thai, Lost Coast, and Afghani cross has a tropical, berry-forward fruity flavor and distinct diesel aroma with strong cherry notes. What starts out as a happy, focused head high that will have you talkative and creatively inspired soon becomes a deeply relaxing body high that leaves you giggly, hungry, and ready for a peaceful night’s sleep. Medical patients report it’s one of the best strains that may help with nausea, stress, anxiety, and chronic pain.
Gorilla Zkittlez
Gorilla Zkittlez is the best strain for nausea if you’re interested in a balanced potent high that blends a blissfully euphoric head high with a relaxing sleepy sedation. This indica-dominant hybrid has a funky fruity flavor, producing a sweet and creamy tropical taste with notes of tobacco, caramel, chocolate, and subtle diesel undertones. Expect the effects of this GG4 and Zkittlez cross to creep up on you slowly before being lifted into a state of euphoria and happiness. This uplifting head high is soon met with a deeply relaxed body high that leaves you sedated and perfectly serene. Gorilla Zkittlez is commonly used by medical cannabis patients for support with nausea, insomnia, anxiety, and depression.
Blue Dream
Blue Dream is a legendary slightly sativa-dominant hybrid with the famous old-school effects that makes classic Cali weed famous. This Blueberry and Super Silver Haze cross originally bred in 2003 has become one of the most popular strains in the world — delivering an instant energetic and focused head high and relaxing body high with zero sedation. This is the best strain for nausea for anyone interested in consuming the most coveted cultivars of all time. Blue Dream is wildly popular with rec consumers, while medical cannabis patients celebrate this icon for its uplifting effects with an uncanny ability to relieve nausea, stress, and mild depression.
How does weed help with nausea?
The way weed helps with nausea all comes down to how THC interacts with the endocannabinoid system (ECS), which is responsible for regulating several physiological processes, including digestive system function. There’s a large body of supporting evidence highlighting the role of the ECS in gastrointestinal function — including inflammation, how food moves through the gut, feeling hungry, and more.
There’s also studies that show ECS dysregulation may lead to intestinal disorders like irritable bowel syndrome, irritable bowel syndrome, and Chron’s disease, each of which can trigger feelings of nausea. Cannabis is said to help regulate ECS imbalance, in turn which could help support these conditions and the nausea they cause.
Are indica or sativa strains better for nausea?
Indica and sativa strains are both known to calm digestive discomfort and ease nausea — with the best strains for nausea depending on the consumer. Individuals experiencing nausea that gets in the way of sleep or are interested in a soothing, relaxed high typically turn to indica-dominant strains to help manage gastrointestinal unease. Those looking for a more energizing experience that offers daytime nausea support will likely find sativa strains the best option. Others turn to the balanced effects of hybrid strains that deliver uplifting cerebral effects combined with physical relaxation.
Does smoking weed offer the best nausea relief?
While more research on the best cannabis products for nausea relief is needed, there is some evidence to support smoking and vaping cannabis offers the most support. One study found flower and concentrates contain the greatest efficacy for nausea relief, with joints associated with better results than weed smoked out of a pipe or vape. High-THC / low-CBD weed strains also showed the greatest relief.
How long does weed take to work for nausea support?
While weed affects everyone differently, most users report significant nausea relief occurs approximately five minutes after smoking flower, vaping, and consuming concentrates.