Hey, bro! 👋
You can already start removing the large developed leaves! But do it on the lower and middle sections of the plant, don’t go up to the tops and growth points (those leaves are really needed up there!).
You can remove up to 1/3 of all fully developed and mature foliage from the middle of the plant at a time. Try not to touch the young leaves that haven't grown yet! Only remove the developed and fully grown leaves that are blocking light from reaching the internodes and new growth points! 👆
But don’t get carried away with defoliation, as the large fan leaves act as batteries for the plant; they are very important for building new buds, internodes, and future flowers! 👆
Good luck, my friend! ✊😇