Looks more like potassium deficiency to me, I think.
Also, I would suggest not blowing the fans directly on the plants, but just over the top of the canopy.
They will waste a lot of energy fighting the wind and this may be a cause for needing extra potassium, to thicken the stems for "wind bracing" needs.
Another also, 18/6 is about perfect for photoperiod plants in vegetative growth.
Cannabis can only grow so much in any 24 hour period, and growth tops out at about 18 hours, meaning running your lights any longer than 18 hours is basically a waste of electricity. Cannabis also needs to "sleep" and undertake certain metabolic processes, and 4 hours "sleep" is probably not enough time for these vital processes to be undertaken. Growth will be superior at 18/6, due to the plant receiving its healthiest light/dark schedule. You will not lose yield or potency by going to 18/6, in fact yield may even increase due to your plants being healthier at 18/6.
Defoliation is a controversial issue with me, I do not believe in it, plants need maximum energy for growth, something that is both wasted and reduced by defoliation. To remove healthy green leaves to then force the plant to regrow new leaves, seems pointless to me (no doubt the plant "thinks" the same thing!). The covered "potential bud sites" (branches really) are relying on those leaves to make the energy they need to grow their best. The small leaves associated with the new growth can in no way produce as much energy a just one healthy green fan leaf. Besides, in 2-5 days, that branch will have grown out from underneath the fan leaf anyhow, making removing it doubly pointless. I have been growing cannabis for 35+ years and am yet to see any cannabis plant that gets rid of its own healthy and green energy producing leaves for no reason or benefit. Cannabis has evolved to grow her biggest and best flowers. Getting rid of perfectly healthy and green energy producing leaves are not part of that process.
Think about how much effort your plant has put into growing those leaves for a reason, now all taken away in a huge waste of effort and energy for that plant. One step forward, two steps back, in my opinion.
Nice set up though, more like a laboratory and indeed an example of careful planning and research. Very nice indeed.
Hope this helps,...........
Organoman.