bottom-up = mobile nutrient.
interveinal chloosis...
Fe deficiency symtpoms, but could be lockout from too much K too. any spots on upper leaves?
is this same as in diary? looks pretty isolated to the bottom. are you allowing any sort of dryback up top? top 1" should be dry before irrigating again. mottled older leaves can happen on their own too. irrigation habits could be part of it. looks like a 1gal pot or smaller? while i don't think it's a cause at moment, your oots will get tight in a small volume and it will make the plant tougher to keep happy/healthy at some point before the end.
need more info to give a good solution. your diary plant looks healthy, relatively speaking. a few leaves shedding at bottom can be no big deal. Soil has unknown amounts of nutes, so it's hard to be definitive on what you should do... if the problem is moving slowly, don't do anything too major. small changes are easier to reset, if wrong... easy to see if they futher slow or alleviate the issue.
if it's developed further up the plant than what is shown in diary, i'd dial back for a fertilization or two and observe and react from there. if it's only the bottom couple nodes shedding, i'd ignore it.
i don't see a need to flush... simply adjust your feed and carry one.. maybe get a little extra runoff with any water-only irrigations between fertilization and that;ll knock it down a peg on its own.