Hello my friend, you should wait till the plant finished stretching and growing. This will be around 2 weeks after you notices the first signs from blooming. When this is done you can make a plan for what leaves you want to defoliate. You only want to defoliate leaves that can cause problems like blocking light or airflow. I like to study my plant, think of the shape and airflow that I want and then mark the leaves that I want to defoliate. Study it one more time if this is really the way to go and then do it. Do not overdo it and leaves that don't block light of airflow should not be defoliated!