I like to strip off at least 50% of the leaves when growing a bushy indica dominant strain. Last year i grew T.H.Seeds Darkstar and it's fan leaves where as big as your whole face. 1 Week before light flip i stripped about 70% of the foliage off of them (i was doing a trellis scrog). Then at day 21, i'll strip off 50% of the foliage, and thats it.
People say it's bad for the plants and that it reduces yield. That taking the big fan leaves off is taking away their ability to make sugars for the area it was plucked from. You know what, i say bullshit. I've been growing weed for ever man. I've experimented with everything, with the exception of aeroponic's and aquaponics, and i say it increases yield significantly. By stripping 50% off the plant, you are opening up more area to absorb the lights and photosynthesize. Plants pull nutrients to wherever it needs it. So if it cant get the building blocks from leaves close by, it will transport the nutrition created by the lower canopy solar panels to the bud sites around the plant, not just in the immediate area.
In my opinion, the only risks are infection from dirty scissors or fingers, or stress induced hermaphrodite
And think about this, if light at bud sites wasn't a factor in bud development, then why do lower bud sites develop whispy airey buds that are badly developed? Wouldn't lower bud sites get first dibs on the juice goin up the roots? The difference is , well, par light, DLI, whatever the fuck you wanna call it. AKA Rate of Photosynthesis..