Hello
@Brent4567 ! Yes you can defoliate at this stage. The point of defoliation is to achieve light penetration, air movement and reduce the waste of plants energy at the lower leaves. So yes you can defoliate. More light penetration will give you more photosynthesis. More air movement will also give you more photosynthesis as the co2 would be able to move better around the canopy and it will reduce the risk of mold (especially at these big colas). Adding another net will not stress them by any means. It would be definitely beneficial to support those big colas but i think that a net is not very practical at this point. It would be more practical to use some yo-yos. At this point your buds are really gaining weight and if you support them you will give them confidence to get really big. Happy growing 👊