Apart from looking like they could use some more nitrogen and a bit under watered, there doesn't seem to be much else wrong.
I would however suggest she is not all that happy and no doubt exhausted by having a 22/2 light schedule, 18/6 is optimum for all cannabis, autos or photos in vegetative growth and your plant will be much healthier and happier if you were to switch to 18/6.
You will not lose yield or potency by going to 18/6, in fact with a happier plant at 18/6, both of these things are likely to increase.
Cannabis does need to sleep and undertake certain metabolic processes that it can not do during the lights on time, and 2 hours of "sleep" is just not enough rest time.
I like to think of the 6 hours of "sleep" as - 2 hours to recover from the day, 2 hours to rest and 2 hours to get ready for the day ahead, and this is basically what occurs during your cannabis plants sleep time and only 2 hours sleep is just not enough sleep for it to be completely happy.
Besides, cannabis can only grow so much in any 24 hour period, and this growth tops out at about 18 hours, meaning running your lights any longer than 18 hours is basically a waste of electricity.
I would also advise against any further defoliation, it just reduces your plants capacity to make energy, thereby slowing growth.
Hope this helps,........
Organoman.