Defoliation of autos is a no no, they're on a clock and do not need added stress from recuperating from a defoliation, if it takes 2 days to recuperate, that's 2 days lost to adding growth. Unless there's a major issue, such as damp leaves touching soil I wouldn't touch them and I've grown some massive autos in my days. Just let time do it's thing and a bit of LST to open stuff up and let them thrive.