Looks like rot. With your set up, it could also just be dirt getting into your res.
Hydroguard to prevent rot, and peroxide to treat it (you'll have to Google the proper amounts). Hydroguard will prevent rot if your res is getting too warm. If you are having real difficulty controlling the res temp and the hydroguard is ineffective, I recommend throwing a few 20oz bottles of frozen water in the res during the hottest parts of the day. Just make sure you really clean the bottles. Good news is this is easy and cheap because once they melt, you just throw them back into your freezer.
As always, keep an eye on your pH.