There is variation in growth patterns, so there is no 1 answer to that question. I have some seeds from 2 inhouse plants that need to be trained until about 10 days into flower before i let it grow vertically (about as extreme as it gets).. or, i end up with a 3' deep canopy and too much larf at the bottom. Other plants need to be ready at flip to flower in order to give my target of 18-24" deep canopy. Relative to my local environmental factors (lights, climate control et al). This is the best zone of buds for me - YMMV, but the variance in growth patterns are not within our control.
You typically want to leave any tie-downs and such until the end. It may seem like it is rigid, but over many weeks it will try to bend back straight, even if slightly it can make the canopy more uneven than it needs to be. I have some plant benders i remove only because the stems will eventually get too thick for them, but then i tie it down with some wire near that bend. A trellis can help too.
So it's a total guessing game unless you've grown the plant before (clones)... the stretchy ones can be HST'd if they outpace shorter plants .. the unusually short ones just suck a dick. if you can use a riser for those to keep them even that's great but using something like a trellis can often make that very difficult once the plant has grown into it.
don't need 40 years to figure this stuff out :P It ain't rocket science.