Hey dude, I would say that it really depends on your taste. I usually wait until all the pistils are either brown or gone, and it tends to coincide with the amber trichomes, but that also depends on the genetics, so it’s up to each person. Euphoric effect, cerebral, milky white, almost amber, and the more amber, the more narcotic. That's my perception. Keep it up and good vibes! 😎